Systemic Lupus Erythematosus (SLE) Induced by Quinidine

Quinidine-induced systemic lupus erythematosus.

SYSTEMIC LUPUS erythematosus (SLE) is a chronic, progressive inflammatory disorder of unknown aetiology affecting connective tissue and producing a disease of great complexity. It probably results from a combination of a predisposition, which may be genetically determined, and recognized or unrecognized precipitating factors (Alarcon-Segovia, 1969). Several precipitants are known, such as sunli...

Monoclonal Antibodies for Systemic Lupus Erythematosus (SLE) †

A number of monoclonal antibodies (mAb) are now under investigation in clinical trials to assess their potential role in Systemic Lupus Erythematosus (SLE). The most frequently used mAb is rituximab, which is directed against CD20, a membrane protein expressed on B lymphocytes. Uncontrolled trials reported an improvement of SLE activity in non-renal patients and other studies even reported an i...

Neurobrucellosis in systemic lupus erythematosus

Background: Brucellosis is a zoonotic infection which is endemic in many countries. It is a multisystem disease which may present with a broad spectrum of clinical manifestations and complications. Neurobrucellosis is an uncommon complication of brucellosis. Case presentation: A 25-year-old woman with a history of lupus for 5 months referred to the emergency ward of Shahid Beheshti Hosp...

Lupus (Systemic Lupus Erythematosus; SLE) — Diagnosis and Treatment

Systemic lupus erythematosus syndrome induced by practolol.

Three patients with angina pectoris treated with practolol in varying doses developed a syndrome of arthralgia, particularly of the small joints of the hands, rash, fever, a raised E.S.R., and positive tests for lupus erythematosus (L.E.) cells and antinuclear antibody. The syndrome responded partly to withdrawal of the drug, but steroids were required to produce adequate symptomatic improvemen...